Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides
نویسندگان
چکیده
منابع مشابه
Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides.
Several reverse transcriptases were studied for their ability to accept anhydrohexitol triphosphates, having a conformationally restricted six-membered ring, as substrate for template-directed synthesis of HNA. It was found that AMV, M-MLV, M-MLV (H(-)), RAV2 and HIV-1 reverse transcriptases were able to recognise the anhydrohexitol triphosphate as substrate and to efficiently catalyse the inco...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2001
ISSN: 1362-4962
DOI: 10.1093/nar/29.15.3154